5-羥色胺抗體產(chǎn)品背景資料英文版展示

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產(chǎn)品名稱  5-羥色胺抗體
產(chǎn)品縮寫  5-HT
蛋 白 名  Serotonin
別    稱  5 HT; 5 hydroxytryptamine; 5HT; Serotonin
免 疫 原  多肽
來(lái)    源  兔
特 異 性  抗人、大鼠、小鼠
克隆類型  多克隆
應(yīng)    用  WB免疫印跡
成    分  200μg/ml親和純化抗體，0.01M PBS，30%甘油。
保存條件  連續(xù)使用時(shí)4°C存儲(chǔ)，保質(zhì)期六個(gè)月；長(zhǎng)期存儲(chǔ)時(shí)建議分裝為10ul以上小包裝-20°C存儲(chǔ)，并避免反復(fù)凍融，保質(zhì)期一年。
背景資料  Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space (>20μm) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with its actions being mediated by a large and diverse range of 5-HT receptors.

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